High-density micro-arrays for mass spectrometry.
نویسندگان
چکیده
Functional high-density micro-arrays for mass spectrometry enable rapid picolitre-volume aliquoting and ultrasensitive analysis of microscale samples, for example, single cells.
منابع مشابه
Carbon-13 labelling strategy for studying the ATP metabolism in individual yeast cells by micro-arrays for mass spectrometry.
Isotopic labelling of cellular metabolites, used in conjunction with high-density micro-arrays for mass spectrometry enables observation of ATP metabolism in single yeast cells.
متن کاملProteome-wide drug screening using mass spectrometric imaging of bead-arrays
A fundamental challenge in the drug discovery process is to develop compounds with high efficacy and minimal side-effects. We describe a new approach to proteome-wide drug screening for detection of on- and off-target binding which combines the advantages of mass spectrometry with microarray technology. The method involves matrix-assisted laser desorption/ionization mass spectrometric imaging (...
متن کاملPerformance of a micro-fabricated Colloid thruster system
In order to fully characterize the performance of the colloid thruster system the electrospray (ES) beam must itself be fully characterized. This may be achieved by measuring various properties such as flow rate, current, droplet/ion charge to mass ratio and current profile. Beam properties of both standard electrospray mass spectrometry (ESMS) emitters and arrays of custom made micro-fabricate...
متن کاملEvaluation of Circular-Shaped Features on the Surface of Solar Cells from the Hubble Space Telescope and EURECA
During post-flight inspection by the manufacturer of the CMX coverglass of the HST solar cells, circular shaped features of unknown origin were discovered. These socalled "droplets" have also been found on samples of the HST and EURECA solar arrays which were sent to the Technical University of Darmstadt for evaluation purposes. They were chemically characterized by electron probe micro analysi...
متن کاملCorrelated matrix-assisted laser desorption/ionization mass spectrometry and fluorescent imaging of photocleavable peptide-coded random bead-arrays
RATIONALE Rapidly performing global proteomic screens is an important goal in the post-genomic era. Correlated matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and fluorescent imaging of photocleavable peptide-coded random bead-arrays was evaluated as a critical step in a new method for proteomic screening that combines many of the advantages of MS with fluorescence-base...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Lab on a chip
دوره 10 23 شماره
صفحات -
تاریخ انتشار 2010